The OPTIMA-Ex trial: Osteoporosis Prevention Through Impact and Muscle-loading Approaches to Exercise

Not Applicable

Active, not recruiting

• Conditions: ow bone mass; Osteopenia; Osteoporosis; Low bone mass; Musculoskeletal - Osteoporosis; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12616001444471
• Lead Sponsor: Griffith University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-10-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Female
Apparently healthy
With lower than average bone mineral density (hip or spine BMD T-score less than or equal to 0)
Unaccustomed to resistance training and impact loading exercise

Exclusion Criteria

Musculoskeletal or medical conditions affecting the ability to perform high intensity physical activity, , medications or medical conditions known to effect bone health, cancer, uncontrolled cardiovascular disease, greater than 2 X-ray’s in the past 12 months and current participation in a regular exercise program known to influence bone or previous competitive or regular participation (more than 1 x per week for 1 year or one full season) in resistance training or boxing (including other fight sports and martial arts), gymnastics/dance sports (gymnastics, ballet, aerobics, cheerleading), court sports (volleyball, basketball, netball), ball sports (Australian rules, rugby league/union, soccer, touch) or racquet sports (badminton, squash, tennis) over the past 4 years.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bilateral proximal femur (femoral neck, trochanter and total hip regions of interest) bone mineral density and 3D variables determined by Dual-energy X-ray Absorptiometry.[All participants, pre (baseline) and post-intervention (10 months).];Lumbar spine (L2-L4) bone mineral density determined by Dual-energy X-ray Absorptiometry.[All participants, pre (baseline) and post-intervention (10 months).];Whole body bone mineral density determined by Dual-energy X-ray Absorptiometry .[All participants, pre (baseline) and post-intervention (10 months)]