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Observational Study on the Application of High-Flow Therapy After Percutaneous Transfemoral Aortic Valve Replacement

Completed
Conditions
Transcatheter Aortic Valve Replacement
Registration Number
NCT04489914
Lead Sponsor
Drägerwerk AG & Co. KGaA
Brief Summary

Percutaneous catheter-assisted valve replacement in aortic position (TAVI) for patients with high perioperative risk has become a standard method in recent years. In addition to the detection of bleeding and cardiac rhythm complications, follow-up care is mainly focused on the monitoring of respiratory parameters after an operation under intubation anesthesia or deep analgosedation. In addition to normal oxygen therapy, non-invasive ventilation and, in case of weaning failure, renewed tracheal intubation in the first 24 h after TAVI have been considered. High flow oxygen therapy (HFOT) now provides a good opportunity to treat patients with a warmed and humidified air-oxygen mixture and to independently control the oxygen content in the inhaled air and the flow in the pharyngeal area.

The aim of the Study is to investigate the Change in oxygenation after high-flow oxygen therapy as a measure of weaning success in postinterventional patients after TAVI.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
25
Inclusion Criteria
  • High-flow oxygen therapy after TAVI
Exclusion Criteria
  • patients without consent
  • age < 18 years

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change of Horovitz index24 hours

The Gradient of paO2/FiO2 will be determined after TAVI via blood gas analysis

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University Schleswig-Holstein

🇩🇪

Lübeck, Germany

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