comparing the effect of two drugs (Dexmedetomidine and lignocaine) in reducing the rise in heart rate, blood pressure during recovery from anaesthesia
Phase 2
- Conditions
- Health Condition 1: null- Age group between 18 and 65years of eithergender belonging to ASAPS 1 or 2 undergoingLaproscopic surgery
- Registration Number
- CTRI/2018/03/012555
- Lead Sponsor
- PG Thesis fund KMC Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
to ASA-PS I and II undergoing elective laproscopic surgeries requiring general anaesthesia and endotracheal intubation
Exclusion Criteria
Suspected allergy to study drugs,
Difficult airway,
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To observe and compare heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure in the periextubation periodTimepoint: Heart rate, Systolic, diastolic and mean arterial pressures at intervals <br/ ><br>Baseline(just before drug administration) <br/ ><br>After 5 min (end of drug administration) <br/ ><br>Post extubation at 1, 2, 3, 4, 5 and 10 min. <br/ ><br>
- Secondary Outcome Measures
Name Time Method Ramsay sedation score <br/ ><br>Time to extubaton <br/ ><br>Any adverse effectsTimepoint: Ramsay sedation score(assessed at intervals of 0min, 5min, 10 min, 30 min, 60 min) <br/ ><br>Time to extubation(time taken from administration of drugs to antagonize residual neuromuscular blockade till the time of removal of endotracheal tube) <br/ ><br>