Measurement of Optic Nerve Sheath Diameter
- Conditions
- Optic Nerve Sheath Diameter
- Interventions
- Other: thoracic epidural catheterization
- Registration Number
- NCT03362255
- Lead Sponsor
- Keimyung University Dongsan Medical Center
- Brief Summary
It is reported that optic nerve sheath diameter increases when higher volume of medication is injected during epidural anesthesia.
This study is designed to compare the optic nerve sheath diameter using 10cc of nomal saline of different speed (3cc/sec vs. 1cc/sec).
- Detailed Description
It is known that insufficient intraoperative or postoperative management can lengthen the hospital stay with unwanted complications. Therefore, active and proper management using continuous thoracic epidural catheterization is suggested good option to prevent such potential complication.
According to previous study, injection of different volume of local anesthetics (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia, high volume of local anesthetics resulted in significant increase of intracranial pressure (ICP). Increase of ICP can reduce regional cerebral flow and oxygen saturation causing the safety of patients. In addition, increase of ICP can result in headache, syncope, and transient loss of visual acuity.
Although it is very invasive method, ICP can be measured directly at the brain parenchyme. Among methods to measure the ICP indirectly, measurement of optic nerve sheath diameter using ultrasound is known to reflect the degree of ICP. It is reported that optic nerve sheath diameter increases when higher volume of medication is injected during epidural anesthesia.
This study is designed to compare the optic nerve sheath diameter using 10cc of nomal saline of different speed (3cc/sec vs. 1cc/sec).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- lung cancer
- liver cancer
- stomach cancer
- pancreas cancer
- coagulopathy
- infection
- previous spine fusion at thoracic level
- previous brain surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Slow speed of injection thoracic epidural catheterization Slow speed of injection (1cc/sec) during thoracic epidurography thoracic epidural catheterization Rapid speed of injection thoracic epidural catheterization Rapid speed of injection (3cc/sec) during thoracic epidurography thoracic epidural catheterization
- Primary Outcome Measures
Name Time Method optic nerve sheath diameter change among 4 time period Baseline, 1 minutes, 10 minutes, 30 minutes after the completion of the intervention optic nerve sheath diameter change among 4 time period using ultrasound
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ji Hee Hong
🇰🇷Daegu, Korea, Republic of