Analysis of Change of Optic Nerve Sheath Diameter in Robot Assisted Laparoscopic Radical Prostatectomy

Not Applicable

Completed

• Conditions: Optic Nerve Sheath Diameter; Robot Assisted Laparoscopic Radical Prostatectomy
• Interventions: Drug: Desflurane; Drug: propofol; Drug: remifentanil

• Registration Number: NCT03152981
• Lead Sponsor: Seoul National University Hospital

Brief Summary

In the present study, The investigators evaluated whether anesthetic agents effects on Optic Nerve Sheath Diameter in patients undergoing Robot Assisted Laparoscopic Radical Prostatectomy

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-04-23
• Status Verified: 2017-05
• Study First Submitted QC: 2017-05-12
• Study First Posted: 2017-05-15
• Study Start: 2017-06-03
• Primary Completion: 2017-12-30
• Study Completion: 2017-12-30
• Last Update Submitted: 2018-04-16
• Last Update Posted: 2018-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

1. Patients undergoing robotic laparoscopic radical prostatectomy
2. Adults 20 to 80 years of age
3. American Society of Anesthesiologists Physical grade 1-2

Exclusion Criteria

1. Patients who did not agree to participate in the study
2. Patients with ophthalmic diseases
3. Patients with previous history of ophthalmic surgery
4. Patients with neurological disorders
5. Patients with history of head surgery due to neurological disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Desflurane group	Desflurane	In desflurane group, desflurane 6-8 vol% and remifentanil (target controlled infusion 2-3 ng / ml) are used for maintenance of anesthesia during surgical procedure
Desflurane group	remifentanil	In desflurane group, desflurane 6-8 vol% and remifentanil (target controlled infusion 2-3 ng / ml) are used for maintenance of anesthesia during surgical procedure
Propofol group	propofol	In propofol group, propofol 3-4 ug/ml and remifentanil 2-3 n /ml using target Controlled Infusion are used for maintenance of anesthesia during surgical procedure
Propofol group	remifentanil	In propofol group, propofol 3-4 ug/ml and remifentanil 2-3 n /ml using target Controlled Infusion are used for maintenance of anesthesia during surgical procedure

Primary Outcome Measures

Name	Time	Method
Optic Nerve Sheath Diameter	1 hour after Trendelenburg position

Trial Locations

Locations (1)

Seoul National Univ. Bundang Hospital; 🇰🇷 Seongnam-si, Gyeonggi-do, Korea, Republic of