NCT05213988Enrolling By Invitation不适用
Effects on GLUcose Homeostasis of Changes in Plasma Lipoproteins Induced by Nutritional and Pharmacologic STrategies Against Diabetes-Related Metabolic Diseases
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Glucose tolerance
研究概览
简要总结
The investigators aim to examine the impact of changes in plasma lipoproteins induced by nutritional and pharmacological interventions on glucose homeostasis
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-65 years
- •both males and females
排除标准
- •acute or chronic conditions influencing glucose and lipid metabolism
- •pregnancy
研究组 & 干预措施
Low-Carbohydrate/High-Protein Diet
Experimental
干预措施: Low-Carbohydrate/High-Protein diet (Dietary Supplement)
Fibrate
Experimental
干预措施: Fibrates (Drug)
Intermittent Fasting
Experimental
干预措施: Intermittent Fasting (Dietary Supplement)
结局指标
主要结局
Glucose tolerance
时间窗: 180 minutes
Glucose tolerance will be measured as the area under the curve of plasma glucose levels in response to a 180-minute 75g oral glucose tolerance test (OGTT)
次要结局
未报告次要终点
研究者
Andrea Natali
Full Professor
Azienda Ospedaliero, Universitaria Pisana
研究点 (1)
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