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Clinical Trials/NCT00181025
NCT00181025UnknownPhase 2

Isolated Pelvic and Limb Perfusion With 1mg TNFa in the Treatment of Locally Advanced Sarcoma of Pelvis and Limbs' Girdle

Gustave Roussy, Cancer Campus, Grand Paris1 site in 1 country33 target enrollmentStarted: May 1, 2004Last updated:
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Conditions
Drugs

Trial Snapshot

Phase
Phase 2
Enrollment
33
Locations
1
Primary Endpoint
Complete response rate on MRI
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This study looks at isolated pelvic perfusion and limbs' girdle with 1 mg tumor necrosis factor alpha (TNFa) in the treatment of locally advanced sarcoma of the pelvis and limbs' girdle.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
16 Years to — (Child, Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Soft tissue or bone sarcomas locally advanced of the pelvis or limbs' girdle

Exclusion Criteria

  • •Resectable tumor without mutilation

Outcomes

Primary Outcomes

Complete response rate on MRI

Secondary Outcomes

  • Histological response
  • Objective responses
  • Rate of conservative treatments
  • Overall survival and disease free survival
  • Local and systemic toxicity

Investigators

Sponsor Class
Other

Study Sites (1)

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