Preoperative Hepatic Arterial Infusion Chemotherapy
- Conditions
- Colorectal Liver Metastases
- Registration Number
- NCT00522509
- Lead Sponsor
- IRCCS San Raffaele
- Brief Summary
To assess the feasibility and results of liver resection after preoperative hepatic artery infusion (HAI) chemotherapy with FUDR.
- Detailed Description
Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative liver resection (HAI group).
Postoperative morbidity, liver function tests, and long term outcomes were evaluated. Adverse events related to HAI chemotherapy were also evaluated.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Unresectable liver metastases
- Potentially resectable liver metastases
Exclusion Criteria
- Extrahepatic disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Surgery - Liver Unit, Scientific Institute San Raffaele,
🇮🇹Milan, Italy