Preoperative chemotherapy followed by hepatic resection for resectable UICC7 StageIIIA, IIIB hepatocellular carcinoma, A phase II clinical trial
Phase 2
Recruiting
- Conditions
- hepatocellular carcinoma
- Registration Number
- JPRN-UMIN000030739
- Lead Sponsor
- Kurume University, Department of Surgery, Division of Hepatobilliary and Pancreatic Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients with history of advanced cancer in other organs within 5 years. 2) A patient who has history of chemotherapy of a regimen including CDDP or 5-FU. 2) Active infectious diseases (except for viral hepatitis) 3) Patients who have a history of allergy to iodine contrast agent, platinum-containing drug, or gelatin-containing drug / food. 4) Pregnant women, breast-feeding women and patients who may be pregnant. Patients who are determined by the attending physician to be inappropriate for this examination for other reasons (in cases where the patient does not obey the instructions or has problems with family cooperation etc.).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The 3 years disease free survival rate after liver surgery
- Secondary Outcome Measures
Name Time Method Overall survival, disease free survival, response to the preoperative chemotherapy, incidence and degree of side effects of preoperative chemotherapy