Restricted Reporting for Positive Urine Cultures

Not Applicable

Completed

• Conditions: Urinary Tract Infection; Bacteriuria
• Interventions: Behavioral: Restricted Reporting

• Registration Number: NCT02797613
• Lead Sponsor: Memorial University of Newfoundland

Brief Summary

Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations. Reducing inappropriate antibiotic use for AB is difficult, since the microbiology laboratory cannot distinguish patients with AB. The investigators study will use a restricted laboratory report requesting the physician to call the laboratory for culture results. The restricted report may reduce the rate of inappropriate treatment of AB.

Detailed Description

Positive urine cultures during the study period will be randomized to restricted microbiology laboratory reporting or standard microbiology laboratory reporting. Physician or patient consent will not be collected. Patient records will be assessed by the investigator to determine if patients have AB or urinary tract infection. Physician antibiotic treatment decision in both groups will be collected.

Study Timeline

• Study First Submitted: 2016-06-08
• Study First Submitted QC: 2016-06-10
• Study First Posted: 2016-06-13
• Study Start: 2017-01-01
• Primary Completion: 2017-05-01
• Study Completion: 2017-05-01
• Results First Submitted: 2019-03-05
• Status Verified: 2020-02
• Results First Submitted QC: 2020-02-26
• Last Update Submitted: 2020-02-26
• Results First Posted: 2020-02-27
• Last Update Posted: 2020-02-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• positive urine culture from inpatients at Health Sciences Centre or St. Clare's Mercy Hospital or outpatients during study period.

Exclusion Criteria

• pregnancy,
• antibiotic treatment at the time of urine collection,
• collection from an indwelling catheter,
• admission to long term care facility.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Restricted Reporting	Restricted Reporting	Microbiology laboratory will report "Positive urine cultures may represent asymptomatic bacteriuria or urinary tract infection. If urinary tract infection is suspected clinically, please call 777-xxxx (researcher mobile phone) for identification and susceptibility results"

Primary Outcome Measures

Name	Time	Method
The Number of Patients Receiving Appropriate Treatment	72 hours from positive culture	Sum of urinary tract infection treated and asymptomatic bacteriuria not treated

Trial Locations

Locations (1)

Health Sciences Center; 🇨🇦 Saint John's, Newfoundland and Labrador, Canada