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临床试验/TCTR20191016001
TCTR20191016001已完成4 期

Effect of budesonide nasal irrigation on Hypothalamus-Pituitary-Adrenal Axis in patients with chronic rhiniosinusitis post endoscopic sinus surgery

ENT department, Chulalongkorn hospital0 个研究点目标入组 22 人开始时间: 2019年10月16日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
22

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 70 Years(—)
性别
All

入选标准

  • 1. Patients with chronic rhinosinusitis with/without nasal polyp who had planned to receive endoscopic sinus surgery with post-operative budesonide nasal irrigation 0.5mg/day or more.
  • 2. Age 18-70 years old

排除标准

  • 1. Patients with pituitary disease, adrenal gland disease, or morbid obesity
  • 2. Patients who received systemic glucocorticoids (intravenous, intramuscular, and oral form) during experiment except for the treatment of chronic rhinosinusitis
  • 3. Patients who had pregnancy.
  • 4. Patients who had medications that effect cortisol.
  • 5. Patients who underwent estrogen therapy or received estrogen oral contraceptive pill.
  • 6. Patients who had abnormal serum morning cortisol before nasal irrigation.

研究者

发起方
ENT department, Chulalongkorn hospital

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