跳至主要内容
临床试验/CTRI/2025/07/091915
CTRI/2025/07/091915尚未招募不适用

To Compare the Impact of Blood Flow Restriction Technique and Muscle Energy Technique on Isokinetic Strength of Quadricep Muscle in Knee Osteoarthritis Patients.

AAKANKSHA DHOK1 个研究点 分布在 1 个国家目标入组 86 人开始时间: 2025年8月6日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
86
试验地点
1
主要终点
Strength (Isokinetic Dynamometer)

研究概览

简要总结

Osteoarthritis (OA) also called as an  Osteoarthrosis or degenerative joint disease, it is the most common form of chronic disorder of synovial joints. In patients with OA knee, pain would be the earliest symptom, and weakness in the quadriceps muscle compared to healthy persons. Quadriceps muscle weakness may contribute to the substantial functional deficit that occur with disease progression.

This study aims to study the impact of Blood flow restriction technique and Muscle Energy Technique on  on isokinetic strength of Quadricep Muscle in knee Osteoarthritis Patients.

GROUP 1 Autogenic Inhibition

Technique Used Post Isometric Relaxation

Protocol

Position Prone, hip flexed to 90°

Isometric contraction of agonist muscle (knee flexors) at 20% strength

Hold for 5 seconds  5 seconds relaxation

2 sets of 5 reps

Frequency 5 sessions per week for 8 weeks

Additional Modalities

Hot Moist Pack  15 mins over knee

Interferential Therapy (IFT)  4 pole method, 20 mins

Ultrasound Therapy 1 MHz, 1.5 W per cm², continuous mode, 5 cm transducer

GROUP 2 Reciprocal Inhibition

Technique UsedReciprocal Inhibition Stretching

Protocol

Position Prone, hip flexed to 90°

Isometric contraction of antagonist muscle (likely knee extensors) at 20% strength

Hold for 5 seconds, 5 seconds relaxation

2 sets of 5 reps

Frequency 5 sessions per week for 8 weeks

Additional Modalities

Hot Moist Pack  15 mins over knee

Interferential Therapy (IFT)  4 pole method, 20 mins

Ultrasound Therapy 1 MHz, 1.5 W per cm², continuous mode, 5 cm transducer

GROUP 3  Blood Flow Restriction (BFR) Technique

Technique Used BFR with Low-Load Resistance Training

Protocol

Application of pneumatic cuff proximally to the target muscle

Pressure induces partial arterial and full venous occlusion

Resistance exercises at 20–30 percentage of 1RM15–30 reps30second rest between sets

Frequency 5 sessions per week for 8 weeks

Additional Modalities

Hot Moist Pack  15 mins over knee

Interferential Therapy (IFT)  4-pole method, 20 mins

Ultrasound Therapy  1 MHz, 1.5 W per cm², continuous mode, 5 cm transducer

Common Interventions in All Group

Hot Moist Pack  Applied for 15 minutes to the affected knee

Interferential Therapy (IFT)  Four-pole vector method, 20 minutes

Ultrasound Therapy  Continuous 1 MHz US at 1.5 W per cm² over knee joint

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
40.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Age 40 to 55 years old.
  • Individuals with grade 2 or 3 for knee OA Kellgren Lawrence grade .
  • Radiographic criteria Presence of osteophytes & Joint space narrowing .
  • Clinical criteria Knee pain , stiffness , limited function , crepitus.
  • Body Mass Index BMI between 18.5 and 40 kg per m².
  • Both Male and Female are included.

排除标准

  • Age Less than 45 years or greater than 55 years Recent knee surgery or arthroscopy Within the past 6 months Knee joint infection or septic arthritis Active or recent infection Severe knee OA Kellgren Lawrence grade
  • Individuals with systemic disorders such as neurological , cardiovascular , respiratory or psychological conditions.
  • Individuals with Cognitive impairment or dementia.
  • Contraindications for BFR training Deep vein thrombosis, peripheral artery disease, or other circulatory impairments.

结局指标

主要结局

Strength (Isokinetic Dynamometer)

时间窗: 8 Weeks

次要结局

  • Range Of motion (Isokinetic Dynamometer)(8 weeks)

研究者

发起方
AAKANKSHA DHOK
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Aakanksha Dhok

Banarsidas Chandiwala Institute of Physiotherapy

研究点 (1)

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