Curcumin-piperine supplementation in children with none- alcoholic fatty liver disease
Phase 3
Recruiting
- Conditions
- one- alcoholic fatty liver disease.Fatty (change of) liver, not elsewhere classifiedK76.0
- Registration Number
- IRCT20121216011763N54
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Children with non alcoholic fatty liver disease
Age 10-18 years old
Exclusion Criteria
Presence of hepatitis, Chronic liver disease , Cardiovascular, Renal, Pulmonary, Hypothyroidism diseases and cancer
Not consuming drugs that could affect on Alanine aminotransferase level including HMG-COA reductase inhibitors, metformin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method C-reactive protein. Timepoint: At the beginning of study - week 10. Method of measurement: Biochemical assessment.;Total antioxidant capacity. Timepoint: At the beginning of study - week 10. Method of measurement: Biochemical assessment.;Total oxidant status. Timepoint: At the beginning of study - week 10. Method of measurement: Biochemical assessment.;Oxidative stress index. Timepoint: At the beginning of study - week 10. Method of measurement: Biochemical assessment.
- Secondary Outcome Measures
Name Time Method Sonographic findings. Timepoint: At the beginning of study - week 10. Method of measurement: Liver ultrasonography.