Evaluation of the effect of curcumin-piperine in the treatment of rheumatoid arthritis
Phase 3
- Conditions
- Rheumatoid Arthritis.Rheumatoid arthritis with rheumatoid factor
- Registration Number
- IRCT20121216011763N53
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Willingness to participate in the study
Age: 30-70 years
Complete informed consent
Rheumatoid arthritis according to the rheumatologist according to the criteria of the American College of Rheumatology 2010
Disease activity score higher than 1/5 and total soft joint count (TJC) and swollen joint count (SJC) higher than 8
Exclusion Criteria
Pregnancy and lactation
Smoking
Heart, lung, kidney, hepatitis, cirrhosis, biliary and immune system disorders, hypertension, diabetes, hypothyroidism, Cushing's syndrome
Weight loss and bariatric surgery in the last year.
Lack of following a special diet and herbal supplements
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total antioxidant capacity (TAC). Timepoint: Beginning and end of the study. Method of measurement: Elisa.;Total Oxidant Status (TOS). Timepoint: Beginning and end of the study. Method of measurement: Elisa.;C-reactive protein (CRP). Timepoint: Beginning and end of the study. Method of measurement: Colorimetric analysis method and by autoanalyzer.;ESR. Timepoint: Beginning and end of the study. Method of measurement: Enzymatic method.;Clinical signs. Timepoint: Beginning and end of the study. Method of measurement: Diagnosis by a specialist.
- Secondary Outcome Measures
Name Time Method