Effect of long-term consumption of kiwifruit on risk factors for disease in healthy subjects.

Not Applicable

Completed

• Conditions: Hyperlipidaemia; Diabetes; Inflammation; Oxidative stress; Cardiovascular - Coronary heart disease; Metabolic and Endocrine - Diabetes; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12616000939493
• Lead Sponsor: ew Zealand Institute for Plant & Food Research Limited

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-15
• Study Completion: 2016-12-13
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 24

Inclusion Criteria

Good health.
No intolerance of kiwifruit.
BMI 20-35 kg/m2
Age 20-60 years.
Willingness to comply with demands of the trial.

Exclusion Criteria

Intolerance of kiwifruit.
Ill health
Glucose intolerance.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma lipid profile: HDL cholesterol, LDL cholesterol, VLDL cholesterol, triglycerides.[Samples will be taken at the end of three weeks lead in, six weeks after starting to consume 2 kiwifruit per day (intervention 1), after three weeks washout, after six weeks of intervention 2, and after three weeks follow up.];HbA1c concentration in blood[Samples will be taken at the end of three weeks lead in, six weeks after starting to consume 2 kiwifruit per day (intervention 1), after three weeks washout, after six weeks of intervention 2, and after three weeks follow up.]

Secondary Outcome Measures

Name	Time	Method
Change in food intakes as a result of consuming 2 kiwifruit per day assessed by a three day food diary[At the end of three weeks lead in, six weeks after starting to consume 2 kiwifruit per day (intervention 1), after three weeks washout, after six weeks of intervention 2, and after three weeks follow up.];Inflammatory biomarkers: C-reactive protein, TNF-a, IL-6 will be measured in plasma samples[Samples will be taken at the end of three weeks lead in, six weeks after starting to consume 2 kiwifruit per day (intervention 1), after three weeks washout, after six weeks of intervention 2, and after three weeks follow up.];Biomarkers of oxidative stress: Total antioxidant capacity, superoxide dismutase, nitric oxide synthase and lactate dehydrogenase will be measured in plasma.[Samples will be taken at the end of three weeks lead in, six weeks after starting to consume 2 kiwifruit per day (intervention 1), after three weeks washout, after six weeks of intervention 2, and after three weeks follow up.]