Effect of ayurvedic treatment on diabetic retinopathy
- Conditions
- Health Condition 1: E113- Type 2 diabetes mellitus with ophthalmic complications
- Registration Number
- CTRI/2023/08/056373
- Lead Sponsor
- All India Institute of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1Patients suffering from Type II DM having Mild to Moderate Non-Proliferative Diabetic Retinopathy
2Patients willing for Ayurveda treatment protocol.
3Patients having history of Diabetes mellitus more than 5 years.
4Patients of DR who have undergone modern medical management and Laser Photocoagulation therapy previously for the same but with persisting symptoms and/or signs will also be included in the study.
5Taking oral hypoglycemic drugs or insulin
1History of glaucoma
2Patients with moderate to severe Cataractous changes.
3Patients having proliferative and advanced Diabetic Retinopathy changes.
4Patients with any other complications of Diabetes like nephropathy and neuropathy.
5Patient having systemic diseases like hypertension, thyroid etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1To assess the retino-protective activity of polyherbal compound in the selected in-vivo model in terms of its anti- angiogenic activity <br/ ><br>2To evaluate the change in the retinal oedema & retinal haemorrhages in patients with Non-Proliferative Diabetic Retinopathy in terms of OCT and Fundus photographs.Timepoint: 80 days including 40 days follow up
- Secondary Outcome Measures
Name Time Method 1.Change in number & size of hard & soft exudates in terms of Fundus photographs. <br/ ><br>2.Change in the quality of ocular health of patients of NPDR in terms of EDTRS visual acuity. <br/ ><br>Timepoint: 80 days including 40 days follow up