Cerebral Oxygenation in Cardiac Arrest and Hypothermia
- Conditions
- Cardiac Arrest
- Registration Number
- NCT01531426
- Lead Sponsor
- Charite University, Berlin, Germany
- Brief Summary
Data indicate that neurological prognostication is difficult after cardiac arrest if mild therapeutic hypothermia is part of the post resuscitation care. Cerebral oxygenation detected by near-infrared spectroscopy, could be a new, non-invasive index marker for outcome assessment after cardiac arrest. The investigators hypothesize that cardiac arrest survivors with a continuously low cerebral oxygenation index have a poor prognosis.
- Detailed Description
The measurement of cerebral oxygen saturation by a non-invasive near-infrared monitor, INVOS® (In-Vivo Optical Spectroscopy; Covidien) can detect changes in oxygen levels reflecting regional blood oxygen saturation of the brain tissue beneath the sensor. If this monitoring can add further information towards reliable prognostication after cardiac arrest is unknown so far.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 94
- over 18 years
- under 18 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method neurological outcome (death; CPC: 5) participants will be followed for the duration of hospital stay, an expected average of 3-6 weeks Cerebral Performance Category 5: death
- Secondary Outcome Measures
Name Time Method neurological outcome CPC 1-5 participants will be followed for the duration of hospital stay, an expected average of 3-6 weeks and a 12 month follow up will be performed CPC 1: Conscious and alert with normal function or only slight disability CPC 2: Conscious and alert with moderate disability CPC 3: Conscious with severe disability CPC 4: Comatose or persistent vegetative state CPC 5: death
Trial Locations
- Locations (1)
Charité Universitätsmedizin
🇩🇪Berlin, Germany
Charité Universitätsmedizin🇩🇪Berlin, Germany