Clinical Characteristics, Treatments, and Outcomes of MI Patients Presenting With Normal ECG

• Conditions: Non-ST Elevated Myocardial Infarction; Electrocardiography

• Registration Number: NCT04710446
• Lead Sponsor: Henan Provincial People's Hospital

Brief Summary

the investigators aimed to analyzed data for hospitalized MI patients with normal ECG.

Detailed Description

The electrocardiogram (ECG) at presentation is a useful tool for risk prediction. Patients with ACS（Acute Coronary Syndromes） and ST-segment depression on ECG have a worse prognosis than patients with a normal ECG. ST-segment depression is not only a qualitative marker, but also a quantitative marker of risk, because the number of leads with ST-segment depression and the magnitude of ST-segment depression (either within a single lead or as sum over all leads) are indicative of the extent of ischaemia and correlate with prognosis.The presence of ST-segment depression \>1 mm in \>_6 leads in conjunction with ST-segment elevation in aVR and/or V1, particularly if the patient presents with haemodynamic compromise, suggests multivessel ischaemia or severe left main coronary artery stenosis. However,in patients presenting without persistent ST-segment elevation,the clinical features, treatments, and outcomes in patients with normal ECG is still unclear.

Study Timeline

• Study Start: 2018-01-01
• Study First Submitted: 2020-12-02
• Study First Submitted QC: 2021-01-12
• Study First Posted: 2021-01-14
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-11
• Last Update Posted: 2022-08-12
• Primary Completion: 2023-01-01
• Study Completion: 2023-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

all patients hospitalized with a principal diagnosis of non-ST-segment elevation infarction (NSTEMI) according to the current ACC/AHA guidelines.

exclusion criteria: end-stage organic disease, thrombotic hematological disorders, and poor echogenicity

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MACE within 1 year	within 1 year	Major Adverse Cardiovascular Events in-hospital within 1 year
MACE within 2 weeks	within 2 weeks	Major Adverse Cardiovascular Events within2 weeks

Trial Locations

Locations (1)

Henan province people's hospital; 🇨🇳 Zhengzhou, Henan, China