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Effect of laser on herpes viruses and on inflammatory mediators in patients with gum disease

Phase 1
Conditions
Health Condition 1: K053- Chronic periodontitis
Registration Number
CTRI/2019/04/018650
Lead Sponsor
Rajarajeshwari Dental College and Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Systematically healthy patients and showing the absence of clinical manifestations of periodontal disease.

2)Chronic periodontitis patients having at least 20 natural teeth and minimum of 6 teeth with periodontal pockets >= 5mm and clinical attachment level >= 3-4mm.

3)All the patients should be systematically healthy and should not have received periodontal treatment for last 6 months prior to the clinical examination and sampling.

Exclusion Criteria

1)Smokers

2)Systemic diseases like diabetes mellitus, heart diseases, rheumatoid arthritis, hepatitis and other systemic diseases that can alter the course of periodontal disease.

3)Diseases of oral hard and soft tissue except caries and periodontitis.

4)Subjects on any medication taken within last 6 months which may alter the periodontal status.

5.Pregnant and lactating mothers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
level of herpes viruses and interferon lambda 1 before and after treatmentTimepoint: baseline, immediately after treatment, at weeks
Secondary Outcome Measures
NameTimeMethod
level of herpes viruses and interferon lambda 1 after scaling and root planing and diode laser therapyTimepoint: baseline, immediately after treatment, at 6 weeks
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