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Repeated corticosteroid injections around the Greater Occipital Nerve (GON) as prophylactic treatment in chronic cluster headache

Phase 1
Active, not recruiting
Conditions
Cluster headache
MedDRA version: 25.0Level: LLTClassification code: 10086874Term: Chronic cluster headache Class: 100000004848
Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
Registration Number
CTIS2024-514311-10-00
Lead Sponsor
eids Universitair Medisch Centrum (LUMC)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Recruiting
Sex
All
Target Recruitment
50
Inclusion Criteria

Age =18, Chronic cluster headache (International Classification of Headache Disorders – third edition; ICHD-3), Ictal pain must be always at the same side, =4 weekly attacks of cluster headache in the prospective one-month baseline observation period, On a stable regimen of cluster headache prophylactics for >4 weeks prior to onset of study treatment and agreeing not to increase the dose and not starting a new cluster prophylactic during the study period

Exclusion Criteria

Contra-indication against, or current use of, corticosteroids, Occipital nerve stimulation (ONS), Use of anticoagulation medication or a known bleeding disorder, Inability to use an electronic diary to monitor individual attacks and other items, Other headaches if the patient cannot reliably distinguish them from attacks of cluster headache, Current use of prophylactic medication for other headaches -, Pregnancy

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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