The effect of calorie-carbohydrate restricted diet compared to a time restricted feeding combined with calorie-carbohydrate restriction on glycemic and appetite biomarkers in type 2 diabetes patients with overweight and obesity: a randomized controlled trial study

Shahid Beheshti University of Medical Sciences0 个研究点目标入组 90 人开始时间: 待定最近更新: 2023年10月16日

适应症

试验速览

暂无简介。

•Men and women 18-65 years old
•Less than 5 years duration of type 2 diabetes (diagnosis based on 2 tests recorded at the diagnostic level, HbA1c and/or blood glucose)
•Use of at least one blood glucose-lowering medication HbA1c more than 43 mmol/mol (6.1%) with hypoglycemic drugs
•Body mass index (BMI) >45 and <27

•Use of insulin
•Use of diabetes drugs from the category of GLP-1 agonists and SGLT-2 inhibitors
•Recent routine HbA1c = 10%
•Weight loss of more than 5 kg in the last 6 months
•Impaired kidney function (eGFR < 60 ml per minute)
•Uncontrolled blood pressure (more than 160 mm Hg systolic or more than 100 mm Hg diastolic)
•Diseases including cancer - heart disease - gout - diagnosed eating disorders - patients with confirmed mental disorders
•Current treatment with Anti-obesity medications
•History of bariatric surgery
•Currently pregnant or lactating, or planning to become pregnant in the next 12 months
•Night shift workers
•Inability to perform physical activities

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