Abnormal serum triglyceride(form of fat)& low HDL cholesterol, important risk factors for heart & blood vessel diseases. Niacin, lipid lowering drug, is less used due to its side effects, can be minimized by adding Laropiprant. We study the drugs effect on both serum triglyceride & low HDL levels
Phase 4
- Conditions
- Health Condition 1: null- Increased triglyceride (more than 300) and its implications with low high density lipoprotein cholesterol (males less than 40 and females less than 45)
- Registration Number
- CTRI/2011/08/001977
- Lead Sponsor
- Sub arm study of PURSE HIS funded by Department of Science and Technology Government of India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Human participants attending cardiology op and PURSE-HIS study, of age group 18 to advanced age with isolated or combined hypertriglyceridemia of both sexes, who have given written informed consent to participate in the study and agree for all presaid examinations
Exclusion Criteria
Pregnant and lactating female participants.
Hypersensitivity to the active substances or to the any of the excipients.
Participants with significant or unexplained hepatic dysfunction.
Active peptic ulcer disease.
Arterial bleeding.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method