NCT00495196已完成不适用
Cardiovascular Response to Peripheral Chemoreceptor Stimulation in Congestive Heart Failure With Cheyne- Stokes Respiration
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- ResMed
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Cardiovascular parameters such as continuous blood pressure and heart rate.
研究概览
简要总结
The purpose of the trial is to investigate the cardiovascular response to peripheral chemoreceptor stimulation in Congestive Heart Failure with Cheyne- Stokes Respiration
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Moderate to severe heart failure (NYHA Class II or above) on optimal medical therapy
- •LVEF less than or equal to 45%
- •Stable condition as defined as no hospital admission or changes to medical therapy within two weeks prior to enrolment
排除标准
- •Patients taking known respiratory stimulants or depressants
- •Clinically significant asthma requiring therapy
- •Significant parenchymal lung disease
- •Primary pulmonary hypertension
- •Myocardial infarction within three months prior to enrolment
- •Patients with cardiac resynchronisation devices and permanent pacemakers
- •Anaemic (haemoglobin < 12g/dL)
结局指标
主要结局
Cardiovascular parameters such as continuous blood pressure and heart rate.
时间窗: During administration of the intervention
次要结局
未报告次要终点
研究者
研究点 (2)
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