Registry Of Acute meDical Emergencies in Brazil

• Conditions: Heart Failure; Chest Pain; Aortic Aneurysm, Familial Thoracic 1; Pulmonary Embolism; Syncope; Acute Coronary Syndromes; Pulmonary Edema
• Interventions: Other: no intervention

• Registration Number: NCT02753023
• Lead Sponsor: University of Sao Paulo General Hospital

Brief Summary

Critical patients in emergency room are seriously situations that need quickly diagnosis and treatment. Different predictors of prognosis can be related with mortality and morbidity in-hospital and in long-term. In Brazil, this kind of registry is not available. The aim of the study is analysis and report data about critical patients in Emergency Departments over all country, showing demographic, clinical and prognosis data about that in Brazil.

Detailed Description

This will be a prospective and multicentric data-bank registry. Initially, all patients with acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), warfarin intoxication, acute pulmonary edema, acute aortic dissection, chest pain, pulmonary embolism and syncope will be included. There will be not exclusion criteria. The inclusion criteria will be followed by definition of each illness described in recent guidelines. Investigators estimated annually over than 500 cases with ACS/chest pain, 300 cases of ADHF, 200 cases of aortic dissection, 200 of pulmonary embolism, 200 cases of warfarin intoxication, 100 cases of syncope and 150 of acute pulmonary edema. Clinical data, electrocardiographic and echocardiographic findings, laboratory results and prognosis will be related. Routine of treatment will be defined by each center. The analysis includes minimum, medium and maximum values. Variables will be adjusted according with each diagnosis and all data will be included using the REDCap digital data entry. Probabilities will be determined by logistic regression and will be considered significate when p \< 0.005. Prospectively, investigators will use the Cox model to calculate associations.

Study Timeline

• Study Start: 2015-05
• Study First Submitted: 2016-04-26
• Study First Submitted QC: 2016-04-26
• Study First Posted: 2016-04-27
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-23
• Last Update Posted: 2018-10-24
• Primary Completion: 2019-01
• Study Completion: 2020-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1650

Inclusion Criteria

• all patients with:
• acute coronary syndromes (ACS) or,
• acute decompensated heart failure (ADHF) or,
• warfarin intoxication or,
• acute pulmonary edema or,
• acute aortic dissection or,
• chest pain or,
• pulmonary embolism or
• syncope.

Exclusion Criteria

-There will be not exclusion criteria.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
acute coronary syndromes	no intervention	No intervention related
acute aortic dissection	no intervention	No intervention related
warfarin intoxication	no intervention	No intervention related
acute pulmonary edema	no intervention	No intervention related
acute decompensated heart failure	no intervention	No intervention related
syncope	no intervention	No intervention related
chest pain	no intervention	No intervention related
pulmonary embolism	no intervention	No intervention related

Primary Outcome Measures

Name	Time	Method
mortality	6 months

Secondary Outcome Measures

Name	Time	Method
mortality	12 months

Trial Locations

Locations (6)

Hospital Unimed Sorocaba; 🇧🇷 Sorocaba, São Paulo, Brazil

Pronto Socorro - Hospital Metropolitano; 🇧🇷 Vitória, Espírito Santo, Brazil

Pronto Atendimento - Hospital Alemão Oswaldo Cruz; 🇧🇷 São Paulo, Brazil

Pronto Socorro - Hospital TotalCor; 🇧🇷 São Paulo, Brazil

Unidade Coronariana do Hospital Estadual Mario Covas; 🇧🇷 Santo André, São Paulo, Brazil

Instituto do Coração - HMFMUSP; 🇧🇷 São Paulo, Brazil