Comparison of two drugs( ropivacaine and levobupivacaine )in children for relief of pain, with regional block (caudal)in surgery below umbilical under general anaesthesia
Phase 2
Recruiting
- Conditions
- Health Condition 1: N399- Disorder of urinary system, unspecified
- Registration Number
- CTRI/2019/08/020801
- Lead Sponsor
- Department of anaesthesia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
pediatric patients of either sex with ASA physical status I&II,
2 to 6 yrs of age undergoing infraumbilical surgery
Exclusion Criteria
local infection at injection site,
Neurological disorders,
allergy to local anaesthetic drug,
sacral or vertebral abnormality,
coagulopathy or anti-coagulation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Quality of analgesia by MOPS Score after administration of 0.25% caudal levobupivacaine <br/ ><br>2. Quality of analgesia by MOPS Score after administration of 0.25% caudal ropivacaine <br/ ><br>3. Duration of post operative analgesia by time to first rescue analgesia.Timepoint: MOPS scoring will be done every 30 minutes for 2 hours after reversal of anesthesia, then hourly till the time first rescue analgesia given
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of ropivacaine and levobupivacaine in post-operative pain management for pediatric infraumbilical surgery?
How does the efficacy of caudal ropivacaine compare to levobupivacaine in pediatric post-operative analgesia under general anesthesia?
Are there specific biomarkers that predict better analgesic response to ropivacaine or levobupivacaine in children with urinary system disorders undergoing infraumbilical surgery?
What are the potential adverse events associated with caudal ropivacaine and levobupivacaine in pediatric patients and how can they be managed?
What are the current drug classes and combination therapies used for post-operative pain relief in pediatric infraumbilical surgeries compared to the approach in CTRI/2019/08/020801?