A prospective randomized study to compare nebulized magnesium sulphate with nebulized lignocaine in attenuating pressor response to laryngoscopy and intubation in patients undergoing general anaesthesia

PT.B.D.SHARMA,PGIMS ROHTAK1 个研究点分布在 1 个国家目标入组 80 人开始时间: 2023年3月10日最近更新: 2023年9月15日

试验速览

阶段: 3 期
状态: 尚未招募
发起方: PT.B.D.SHARMA,PGIMS ROHTAK
入组人数: 80
试验地点: 1
主要终点: TO ASSESS EFFICACY OF NEBULIZED MAGNESIUM SULPHATE IN COMPARISON TO NEBULIZED LIGNOCAINE ON HYPERTENSIVE TACHYCARDIA RESPONSE TO LARYNGOSCOPY ANMD INTUBATION DURING GENERAL ANAESTHESIA

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

ASA 1 and 2 patients of either sex aged 18 to 60 years scheduled for elective surgery under general anaesthesia requiring endotracheal intubation will be nebulized, group-M (40 patients) with 5 ml solution containing 500 mg magnesium sulphate in normal saline and group-L (40 patients) with 5ml of 2% lignocaine to attenuate pressor response to laryngoscopy and intubation.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 18.00 Day(s) 至 60.00 Day(s)（—）
性别: All

入选标准

•ASA Grade I and II patients of either sex in age group of 18-60 years posted for surgery under general anaesthesia, who are either sex and willing to participate will be included in this study.

排除标准

•patients with refusal of consent, history of hypertension, patients having cardiovascular dysfunction, epilepsy, pregnancy, anticipated difficult airway, patients with known history of allergy to study drug.

结局指标

主要结局

TO ASSESS EFFICACY OF NEBULIZED MAGNESIUM SULPHATE IN COMPARISON TO NEBULIZED LIGNOCAINE ON HYPERTENSIVE TACHYCARDIA RESPONSE TO LARYNGOSCOPY ANMD INTUBATION DURING GENERAL ANAESTHESIA

时间窗: AFTER INTUBATION 1MIN,3MIN,5MIN

次要结局

TO EVALUATE SIDE EFFECTS ASSOCIATED WITH USE OF THESE DRUG,IF ANY1.HYPOTENSION 2.BRADYCARDIA 3. FALL IN SATURATION 4.ANY OTHER(WITHIN 30 MIN)

研究者

发起方

PT.B.D.SHARMA,PGIMS ROHTAK

申办方类型

Government medical college

研究点 (1)

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