Multimodal prospective analysis of biomarkers for Critical-Illness-Polyneuromyopathy on patients directly after ICU treatment
Suspended
- Conditions
- G62.80G72.80
- Registration Number
- DRKS00012739
- Lead Sponsor
- Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
voluntariness; written confirmed consent; adequate knowledge of German language; at least 18 years of age, = 7 days current stay on ICU incl. at least 3 days ventilation
Exclusion Criteria
< 18 years; withdrawal of agreement; employees of the researching medic or the facility that is partipicipating in this clinical research or other studies; simultaneous participation in an AMG-study; CCM: ophthalmic surgery within the last 3 months, MRI: metal implants, QST: skin disorder in area of investigation
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of CIPNM (Critical-Illness-Polyneuromyopathie); frequency of abnormal parameters in ENG (elektroneurography), EMG (elektromypgraphy), CCM (confocal corneale microscopy), QST (quantitative sensory testing), MRT (Magnetic resonance imaging), skin biopsy; determination of sensitivity and specificity of individual parameters each for the three timepoints: directly, 3 and 12 month after ICU-treatment.
- Secondary Outcome Measures
Name Time Method correlation of values of all investigations among each other