SMR/Theta Neurofeedback Training Improves Cognitive Performance and EEG Activity in Elderly With Mild Cognitive Impairment: A Pilot Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Mild Cognitive Impairment
- Sponsor
- Fabienne Marlats
- Enrollment
- 20
- Primary Endpoint
- Rey Auditory Verbal Learning test
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
This is a non-pharmacological pilot study showing the improvement of a SMR/theta neurofeedback training program on cognitive performance and EEG activity in Elderly with Mild Cognitive Impairment.
Detailed Description
Neurofeedback training (NF) as self-regulation method of brain activity, may be beneficial in elderly with mild cognitive impairment. In this pilot study, the investigators studied whether a sensorimotor(SMR)/theta NF training could improve cognitive performance and brain electrical activity in a sample group of elderly patients with mild cognitive impairment. Twenty participants performed an electroencephalography recording, a battery of neuropsychological tests before the neurofeedback training program (T0), following the neurofeedback training program (T1) and 1-month follow-up (T2).
Investigators
Fabienne Marlats
Neuropsychologist
Broca Hospital
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of Mild Cognitive Impairment
- •education level of 9 years of studies minimum
- •righthandedness
- •subjective memory complaint confirmed by an informant
- •a Mini Mental Status Examination score \>
- •preserve activity of daily living and absence of dementia.
Exclusion Criteria
- •elderly persons who were under guardianship
- •resident in nursing facilities
- •neurological disease, psychiatric disease
- •and involved in another cogniitve intervention.
Outcomes
Primary Outcomes
Rey Auditory Verbal Learning test
Time Frame: Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up
Assessment of verbal learning in episodic memory, evaluating the ability to encode, combine, store and long-term consolidation process.
Secondary Outcomes
- Relative power for delta, theta, alpha, sensorimotor and lower beta frequency bands.(Assessment at baseline, change from baseline to 11 weeks immediately after the NF training and 1 month follow-up)