Pilot Study Evaluating the Effectiveness of Neurofeedback Training in the Improvement of Cognitive Functions of the Elderly With Mild Cognitive Impairment
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Mild Cognitive Impairment
- 发起方
- Assistance Publique - Hôpitaux de Paris
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change on Rey Auditory Verbal Learning test
- 最后更新
- 6年前
概览
简要总结
The purpose of this study is to evaluate the effects of SMR neurofeedback training on cognitive performance and electrical brain activity in elderly with cognitive impairment.
详细描述
Older adults with Mild Cognitive Impairment (MCI) are at high risk to progress to Alzheimer's disease (AD). Slowing down effect of dementia by enhancing brain plasticity represents on of the most prominent challenges. Neurofeedback is one of the promising techniques that showed therapeutic efficacy and cognitive improvement in attention-deficit hyperactivity disorder, epilepsy, stroke. The investigators aim to study the effects of a sensorimotor neurofeedback training protocol (SMR) on cognitive performances in elderly and to assess whether MCI patients change in brain electrical activity after training.
研究者
入排标准
入选标准
- •Clinical diagnosis of Mild Cognitive Impairment, educational level of 9 years of studies minimum, righthandedness, subjective memory complaint confirmed by an informant, a mini mental Status Examination score \> 20, preserve activity of daily living and absence of dementia.
排除标准
- •Elderly persons who were under guardianship, resident in nursing facilities, neurological disease, psychiatric disease and involved in another cognitive intervention.
结局指标
主要结局
Change on Rey Auditory Verbal Learning test
时间窗: Baseline assessment in 2 weeks period before intervention, change from baseline at immediately after the end of the intervention , and after 1-month follow-up
Assessment of Verbal learning in episodic memory
次要结局
- relative power for delta, theta, alpha, sensorimotor and lower beta frequency bands.(assessment at baseline, change from baseline to immediately after the NF training and 1 month follow-up)