Sugammadex for prevention of postoperative pulmonary complications

Phase 3

• Conditions: Elective or emergency major abdominal or non-cardiac thoracic surgery; Surgery

• Registration Number: ISRCTN15109717
• Lead Sponsor: Belfast Health and Social Care Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-12-21
• Last Update Posted: 18 March 2024
• Study Completion: 2026-11-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 2500

Inclusion Criteria

1. Patients presenting for elective or emergency major abdominal or non-cardiac thoracic surgery
2. Age =50 years
3. Planned use of rocuronium or vecuronium for neuromuscular blockade
4. Planned reversal of neuromuscular blockade at the end of surgery

Exclusion Criteria

1. Known allergy to sugammadex, neostigmine or glycopyrrolate
2. Lack of written informed consent for trial participation
3. Planned invasive mechanical ventilation before or after surgery
4. Previous participation in SINFONIA trial
5. Clinician refusal (with reason)

Study & Design

• Study Type: Interventional
• Study Design: Not specified