Evaluation of Root Coverage by Subepithelial Connective Graft Associated to Root Conditioning by Citric Acid Plus Tetracycline and Antimicrobial Photodynamic Therapy: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- Total root coverage measured with a periodontal probe in mm
研究概览
简要总结
The aim of this study was to evaluate the effect of two root-conditioning agents used in conjunction with subepithelial connective graft technique on root coverage outcomes. One is citric acid plus tetracycline and the other is antimicrobial photodynamic therapy.
详细描述
Citric acid plus tetracycline has properties of root surface decontamination, surface demineralization and exposure of collagen fibers.
Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The outcome assessor did not have access to patient's records
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Gingival recession - Miller's class I or II (2 to 5 mm of height) at least in one tooth
- •Indication of root coverage by dentin hypersensitivity or esthetic
排除标准
- •Pregnancy
- •Systemic medication use that could impair wound healing or surgery procedure
- •Systemic diseases as diabetes, uncontrolled hypertension, coagulation diseases, kidney diseases.
研究组 & 干预措施
Control
Root treatment with scaling and root planing.
干预措施: Control (Procedure)
Citric acid plus tetracycline
Root treatment with 50% citric acid plus 10% tetracycline, pH1, passive application for 90s.
干预措施: citric acid plus tetracycline (Procedure)
Antimicrobial photodynamic therapy
Antimicrobial photodynamic therapy with toluidine blue O (100ug/ml - 60s pre-irradiation - pH4) and red laser (660nm, 30 milliwatts, 45 joules per square centimeter, sweeping mode, 90s)
干预措施: antimicrobial photodynamic therapy (Procedure)
结局指标
主要结局
Total root coverage measured with a periodontal probe in mm
时间窗: one year
Distance from cemento-enamel junction to gingival margin = 0 mm
次要结局
- Keratinized mucosa width measured with a periodontal probe in mm(one year)
- Dentin hypersensitivity measured by applying an air jet on teeth and patient fills up a visual analogue scale(one year)
研究者
Carla Andreotti Damante
Associate professor
University of Sao Paulo