Does Increase in Appetite After Iron Treatment Induced by Ghrelin Hormone
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 111
- 试验地点
- 1
- 主要终点
- Ghrelin levels after treatment with Intravenous Iron
研究概览
简要总结
The purpose of this study is to examine whether iron therapy in patients with intravenous iron deficiency anemia causes an increase in appetite. And whether this increase is mediated by the hormone ghrelin.
详细描述
Prior to Iron treatment Investigator will sample subject blood for: counting blood, iron sector indices, renal function, electrolytes, and measure the level of ghrelin fasting plasma. In addition, the patient will fill a structured questionnaire that examines appetite levels. participants will be asked to answer a structured questionnaire which will include information on demographics, clinical data (fever, allergies, weight, height) and comorbidities. Additional data on laboratory tests, comorbidities, medication and regular blood and urine cultures results will be taken from the medical file. Iron treatment will be given according to local standard procedure . At the end of the treatment ghrelin levels and questionaire will be retaken .
iron deficiency anemia is defined: hemoglobin <12 gr / dl in women and Hb <13 gr / dl in men with ferritin <15 ng / ml.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Iron deficiency anemia that wasn't responded to oral treatment or wasn't tolerable due to side effects
- •sign and dated informed consent form.
排除标准
- •chronic inflammatory disease.
- •chronic renal failure
- •active cancer.
- •active Infectious disease.
- •non iron deficiency anemia.
- •pregnancy.
结局指标
主要结局
Ghrelin levels after treatment with Intravenous Iron
时间窗: 12 weeks
次要结局
未报告次要终点
