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临床试验/NCT02734641
NCT02734641已完成不适用

Does Increase in Appetite After Iron Treatment Induced by Ghrelin Hormone

HaEmek Medical Center, Israel1 个研究点 分布在 1 个国家目标入组 111 人开始时间: 2016年8月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
111
试验地点
1
主要终点
Ghrelin levels after treatment with Intravenous Iron

研究概览

简要总结

The purpose of this study is to examine whether iron therapy in patients with intravenous iron deficiency anemia causes an increase in appetite. And whether this increase is mediated by the hormone ghrelin.

详细描述

Prior to Iron treatment Investigator will sample subject blood for: counting blood, iron sector indices, renal function, electrolytes, and measure the level of ghrelin fasting plasma. In addition, the patient will fill a structured questionnaire that examines appetite levels. participants will be asked to answer a structured questionnaire which will include information on demographics, clinical data (fever, allergies, weight, height) and comorbidities. Additional data on laboratory tests, comorbidities, medication and regular blood and urine cultures results will be taken from the medical file. Iron treatment will be given according to local standard procedure . At the end of the treatment ghrelin levels and questionaire will be retaken .

iron deficiency anemia is defined: hemoglobin <12 gr / dl in women and Hb <13 gr / dl in men with ferritin <15 ng / ml.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Iron deficiency anemia that wasn't responded to oral treatment or wasn't tolerable due to side effects
  • sign and dated informed consent form.

排除标准

  • chronic inflammatory disease.
  • chronic renal failure
  • active cancer.
  • active Infectious disease.
  • non iron deficiency anemia.
  • pregnancy.

结局指标

主要结局

Ghrelin levels after treatment with Intravenous Iron

时间窗: 12 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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