BLOOD BNP AND UTERINE ARTERY PRESSURE CHANGES IN PREGNANT WOMEN WITH HIGH BLOOD PRESSURE

Not Applicable

• Conditions: Health Condition 1: O149- Unspecified pre-eclampsia

• Registration Number: CTRI/2022/02/040520
• Lead Sponsor: MAULANA AZAD MEDICAL COLLEGE AND LOK NAYAK HOSPITAL NEW DELHI

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1)Singleton pregnancy with no gross congenital anomaly in level II scan.

2) Patients after 20 weeks period of gestation with excellent dates as corroborated by

a) Clinical information of known last menstrual period

b) 28 to 30 days cycle

c) Availability of first trimester ultrasound

3a) Cases: Pregnant female included in the study as case are women who are diagnosed as preeclampsia with new onset hypertension after 20 weeks of gestation associated with proteinuria

3b) Controls: Pregnant female included in the study as control are normotensive women whose pregnancies.

(Controls will be matched for Period of Gestation (POG) with cases in 1:1 ratio)

Exclusion Criteria

known case of heart disease

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum NT pro BNP level <br/ ><br> Uterine Artery Doppler PI <br/ ><br>Timepoint: 1 year <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
Adverse maternal Outcome: <br/ ><br>1.Eclampsia <br/ ><br>2.HELLP <br/ ><br>3.Acute kidney injury <br/ ><br>4.Pulmonary edema <br/ ><br>5.Intracranial haemorrhage <br/ ><br>Adverse perinatal outcome which will be defined by any one of: <br/ ><br> 1.Low birth weight(LBW) <br/ ><br> 2. APGAR7 at 5 minutes after birth <br/ ><br> 3. Cesarean Section for intra-partum fetal compromise (CS-IFC) <br/ ><br> 4. Meconium Stained Liquor (MSL) <br/ ><br> 5. Admission to NICU for Hypoxic Ischemic Encephalopathy <br/ ><br> 6. Intrauterine Fetal Death (IUD) <br/ ><br> 7. Cord Blood pH 7 <br/ ><br>Timepoint: 1 year