A Comparative Evaluation of Effect of Dexamethazone on Postendodontic Pain and Success of Inferior Alveolar Nerve Block in Mandibular Molars With Symptomatic Irreversible Pulpitis
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Postoperative pain
研究概览
简要总结
A Comparative Evaluation of the effect of pretreatment dexamethasone versus placebo on post-endodontic pain and success of inferior alveolar nerve block in Mandibular molars with symptomatic Irreversible Pulpitis: A Blinded Randomized Clinical Trial Therapeutic study
详细描述
Participants, Interventions and Outcome
Setting:
Patients are of the clinic of endodontics at the faculty of oral and dental medicine, Cairo University, Urban area, Cairo governorate, Egypt.
- The dental Unit is Adec 200 U.S.A.
- The x-ray Machine is ViVi, S.r.I, Italy
- The x-ray films are Kodac, speed D, size 2.
- The operators are master degree students in the department of Endodontics.
- No dental assistant
- Time: 2017-2016
Procedure steps:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
盲法说明
investigator
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients in good health with no systemic disease (American Society of Anesthesiologists Class II)
- •Patients having symptomatic irreversible pulpitis in one of their mandibular molars
- •Age range is between 20 and 50 years
- •Patients who can understand the categorical tool (points) for measurement
- •Patients able to sign informed consent
排除标准
- •Patients with positive percussion test
- •Patients having history of necrosis with or without apical pathosis
- •Patients have sinus tract or fistula extraoral or intraoral
- •Patients having active pain in more than one molar
- •Patients who had taken analgesics in the 12 hours preceding the preparation.
- •Complicating systemic disease
- •Subjects with allergies and hypersensitivity to or unable to take dexamethasone
- •Teeth with grade 2 or 3 mobility
研究组 & 干预措施
Drug dexamethasone
preoperative single dose of dexamethasone 0.5 mg oral tablet given to patients before starting of root canal treatment by 30 minutes.
干预措施: Dexamethasone Oral Tablet (Drug)
Placebo
Placebo will be administrated to patients before stating of root canal treatment
干预措施: Placebo (Drug)
结局指标
主要结局
Postoperative pain
时间窗: 48 hours
Numerical rating scale
次要结局
- success of inferior alveolar nerve block(2 hours)
研究者
Mai Mohamed Safei Eldin Sayed
Principle investigator
Cairo University