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The safety and clinical efficacy of electro-thumbtack needle in the prevention of acute mountain sickness : a prospective, randomised, controlled study

Early Phase 1
Recruiting
Conditions
Acute mountain sickness
Registration Number
ITMCTR2023000065
Lead Sponsor
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. The subject is at an altitude of >= 3000m during the test;
2. The subject has not arrived on the plateau for more than 48 hours;
3. l LLSS score >= 3 and at least 1 headache;
4. Age >= 18 years and < 65 years;
5. No experience of living and working in a plateau within 2 months;
6. Not having participated in another clinical trial within 3 months;
7. Voluntary participation in this study and signed informed consent.

Exclusion Criteria

1. 2 weeks before entering the plateau with dizziness, chronic headache, cardiovascular and cerebrovascular diseases, chronic respiratory diseases, chronic digestive system diseases;
2.combined with other serious diseases such as malignant tumors and mental illnesses and other diseases that affect the evaluation of this study;
3.Those who are contraindicated to electro-snap needling: such as those who have cardiac pacemakers;
4. taking preventive drugs (including acetazolamide, dexamethasone, nifedipine and phosphodiesterase-3 inhibitors) within 2 weeks before plateauing.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of AMS;
Secondary Outcome Measures
NameTimeMethod
Bp;Oxygen saturation;Microcirculation indicators;VAS of headache;HR;the severity of AMS;GSQS;SSS;LLSS;AMS clinical function score;
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