NL-OMON52847招募中不适用
Respiratory muscle training in patients with Spinal Muscular Atrophy - RESISTANT
niversitair Medisch Centrum Utrecht0 个研究点目标入组 50 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2 至 64(—)
入选标准
- •* Patients with SMA aged >= 8 years with respiratory muscle weakness (Maximal
- •inspiratory pressure < -80 cmH2O) will be invited to participate.
- •Both patients without respiratory support and patients on night-time
- •non-invasive ventilatory support are eligible.
- •* Patients who are treated with Spinraza® for more than 2 months and patients
- •who are not/or will not be treated with Spinraza® .
排除标准
- •* tracheostomy,
- •* inability to perform respiratory and/or lung-function testing,
- •* inability to understand Dutch or English,
- •* patients who are mentally incompetent,
- •* patients with a history of pneumothorax or symptomatic low cardiac output
- •* patients who start Spinraza during trial
研究者
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