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临床试验/NL-OMON52847
NL-OMON52847招募中不适用

Respiratory muscle training in patients with Spinal Muscular Atrophy - RESISTANT

niversitair Medisch Centrum Utrecht0 个研究点目标入组 50 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
50

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
2 至 64(—)

入选标准

  • * Patients with SMA aged >= 8 years with respiratory muscle weakness (Maximal
  • inspiratory pressure < -80 cmH2O) will be invited to participate.
  • Both patients without respiratory support and patients on night-time
  • non-invasive ventilatory support are eligible.
  • * Patients who are treated with Spinraza® for more than 2 months and patients
  • who are not/or will not be treated with Spinraza® .

排除标准

  • * tracheostomy,
  • * inability to perform respiratory and/or lung-function testing,
  • * inability to understand Dutch or English,
  • * patients who are mentally incompetent,
  • * patients with a history of pneumothorax or symptomatic low cardiac output
  • * patients who start Spinraza during trial

研究者

发起方
niversitair Medisch Centrum Utrecht

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