Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients With Painless Gastroscopy

Not Applicable

Completed

• Conditions: Hypoxemia
• Interventions: Other: Oxygen delivery mode

• Registration Number: NCT06139081
• Lead Sponsor: Nanjing First Hospital, Nanjing Medical University

Brief Summary

In this study, patients undergoing painless gastroscopy were selected to change the nasal catheter oxygen delivery mode to oral oxygen delivery after endoscope implantation, in order to explore the effect of this oxygen delivery mode on the incidence of hypoxemia during general anesthesia gastroscopy.

Detailed Description

This study was a randomized controlled study in which patients undergoing elective painless gastroscopy were selected and grouped by random number table. The control group used conventional nasal cannula oxygen method: nasal cannula was used before and after gastroscopy was implanted and after withdrawing from the gastroscopy. Test group: nasal cannula nasal oxygen before gastroscopy placement, nasal cannula oxygen delivery after gastroscopy placement, nasal cannula nasal oxygen delivery after exit gastroscopy, nasal cannula nasal oxygen after exiting gastroscopy. The incidence of intraoperative hypoxemia was observed.

Study Timeline

• Study Start: 2023-09-22
• Study First Submitted: 2023-10-26
• Study First Submitted QC: 2023-11-16
• Study First Posted: 2023-11-18
• Status Verified: 2024-11
• Primary Completion: 2024-12-13
• Study Completion: 2024-12-14
• Last Update Submitted: 2025-01-12
• Last Update Posted: 2025-01-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 648

Inclusion Criteria

Patients who receiving gastroscopy under general anesthesia, accompanied with one of the following risk factors of hypoxia:

1. Patients combined with heart or respiratory diseases
2. Age older than 60
3. ASA grading II-III
4. BMI≥30kg/m²,
5. Snoring or having sleep apnea syndrome
6. Patients with a STOP-Bang score ≥ 3 (the risk of OSAS is high) are considered to be highly risk of hypoxia.

Exclusion Criteria

1. Severe cardiovascular, pulmonary, liver, or kidney disease
2. Patients with infections or tumors of airway
3. History of difficult intubation under general anesthesia
4. Severe sleep apnea syndrome [hypopnea/apnea hypopnea index (AHI)>40]
5. Patients allergic to propofol, eggs, soy or egg whites
6. Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group A	Oxygen delivery mode	Transnasal oxygen was administered by nasal catheter before gastroscopy, transoral oxygen was administered by nasal catheter during gastroscopy, and transnasal oxygen was administered by nasal catheter after withdrawal of gastroscope.

Primary Outcome Measures

Name	Time	Method
Incidence of hypoxemia	Five minutes after finishing gastroscopy examination	SpO2\<92%

Trial Locations

Locations (1)

Nanjing First Hospital; 🇨🇳 Nanjing, Jiangsu, China