High Flow Nasal Cannula and Diaphragmatic Function

Not Applicable

Completed

• Conditions: Diaphragm Injury; Postoperative Complications
• Interventions: Device: High flow nasal cannula; Device: Facial mask

• Registration Number: NCT05532033
• Lead Sponsor: Università degli Studi di Ferrara

Brief Summary

Prospective randomized study investigating the effect of postoperative oxygen delivery on diaphragmatic function. Two different modalities of oxygen delivery will be compared: high flow nasal cannula versus standard oxygen therapy with facial mask

Detailed Description

Not available

Study Timeline

• Study Start: 2022-08-09
• Study First Submitted: 2022-08-09
• Study First Submitted QC: 2022-09-07
• Study First Posted: 2022-09-08
• Status Verified: 2023-10
• Primary Completion: 2023-10-15
• Study Completion: 2023-10-22
• Last Update Submitted: 2023-10-22
• Last Update Posted: 2023-10-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• Patients scheduled for elective thoracic surgery

Exclusion Criteria

• ASA score >3
• Body mass index > 35 kg/m2
• History of neuromuscular disease
• History of thoracic surgery
• Phrenic nerve paisy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
high flow nasal cannula	High flow nasal cannula	Two hours after extubation patients will received high flow nasal cannula oxygenation therapy for 24 hours
Standard oxygen therapy	Facial mask	Two hours after extubation patients will received standard oxygenation therapy for 24 hours

Primary Outcome Measures

Name	Time	Method
Incidence of diaphragmatic dysfunction	24 hours after surgery	Ultrasound evaluation of diaphragmatic dysfunction

Secondary Outcome Measures

Name	Time	Method
Postoperative pulmonary complication	7 days after surgery	Incidence of postoperative pulmonary complication

Trial Locations

Locations (1)

Università di Ferrara; 🇮🇹 Ferrara, Italy