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Clinical Trials/NCT04023838
NCT04023838
Unknown
Not Applicable

Randomized Comparison of Radiation Exposure in Coronary Angiography Between Right Conventional and Left Distal Radial Artery Approach: The DOSE Trial

Chonnam National University Hospital0 sites100 target enrollmentStarted: August 2019Last updated:

Overview

Phase
Not Applicable
Enrollment
100
Primary Endpoint
Radiation dose of the operator (µSv)

Overview

Brief Summary

Randomized comparison of radiation exposure in coronary angiography between right conventional and left distal radial artery approach

Detailed Description

The left snuffbox approach is expected to be easier to perform because of less severe tortuosity of the clavicle artery. However, clinical validation of the snuffbox approach was not completed compared with the conventional radial approach. Especially, there is no clinical data on the comparison of the radiation dose in both approaches. To date, there have been some studies on the radiation dose between the left and right radial artery and femoral artery puncture site, but no studies have been conducted on the left snuffbox approach.

The purpose of this study was to compare the radiation doses of the two interventional radiologists by randomly assigning coronary angiography to the left snuffbox approach and right conventional radial approach.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients who are a palpable right radial artery and left distal radial artery
  • The decision to participate voluntarily in this study and the written consent of the patient

Exclusion Criteria

  • Patients who are not palpable right radial artery and left distal radial artery
  • Patients who have arteriovenous fistula
  • Patients presenting with acute myocardial infarction
  • Patients who need to perform coronary angiography via femoral approach, such as shock state
  • Patients who have atrioventricular block on the electrocardiogram
  • Patients who have a plan to perform Ergonovine provocation test
  • Patients who need percutaneous coronary intervention
  • Patients who are not appropriate for this study

Outcomes

Primary Outcomes

Radiation dose of the operator (µSv)

Time Frame: Through procedure completion, up to 6 hours

Radiation dose (µSv) of the operator's head, hand, and body will be compared between right conventional radial artery approach and left snuffbox approach group.

Secondary Outcomes

  • Fluoroscopy time for coronary angiography (second)(Through procedure completion, up to 6 hours)
  • Dose-area product (mGy*cm2)(Through procedure completion, up to 6 hours)
  • Success rate of radial puncture (%)(Through procedure completion, up to 6 hours)
  • Hemostasis duration (minute)(During hospitalization, up to 1 month)
  • Cannulation time (second)(Through procedure completion, up to 6 hours)
  • Puncture site complication after hemostasis(During hospitalization, up to 1 month)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Myung Ho Jeong

Professor

Chonnam National University Hospital

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