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临床试验/CTRI/2024/04/066479
CTRI/2024/04/066479已完成4 期

Comparision of Desflurane and Propofol for emergence and recovery characteristics in adult patients undergoing lumbar spine surgeries under general anaesthesia.

Kranthi Kumar Nannapaneni1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2024年5月23日最近更新:

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
90
试验地点
1
主要终点
Comparing “Modified Aldrete Score” between both the groups after extubation.

研究概览

简要总结

The proposed randomized controlled study will be conducted in the Department of Anaesthesia at Command Hospital (Air Force) Bengaluru. This study will be conducted on the patients undergoing lumbar surgeries under General Anaesthesia over a period of 18 months after approval from the Institutional ethical committee. Patients will be explained in detail regarding the study in their vernacular language and written informed consent will be obtained from them. All the 90 patients will be randomized using a computer-generated algorithm and concealment done using opaque sealed envelope into two groups with 45 patients in each group [n=45]. Group D patients will be receive Desflurane as the anaesthetic agent for maintenance of anaesthesia and Group P patients will receive Propofol as the anaesthetic agent for maintenance of anaesthesia. Demographic and clinical data including age, sex, height, weight, etc. will be recorded for all the patients. American Society of Anesthesiology (ASA) physical status, comorbidities and medications, if any will be noted. Recovery in the postoperative period will be compared in both the groups using "Modified Aldrete Score" which will be recorded at 10, 20 and 30 minutes after extubation in the post anaesthesia care unit. Comparing desflurane and propofol as an anaesthetic agent in spine surgeries can provide valuable insights into optimizing anesthetic plans, tailoring them to the specific demands of extended surgical procedures and ultimately contributing to enhanced patient care.

研究设计

研究类型
Interventional
分配方式
Randomized

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients undergoing lumbar spine surgeries under General Anaesthesia.
  • ASA physical status I and II.

排除标准

  • Significant cardiovascular , respiratory, hepatic, renal, neurological, psychiatric or metabolic.
  • Documented allergic reaction to the anaesthetic agent being used.

结局指标

主要结局

Comparing “Modified Aldrete Score” between both the groups after extubation.

时间窗: AT 10Min, 20Min and 30Min

次要结局

  • Compare time to extubation, spontaneous eye opening & response to verbal commands after switching off the anaesthetic agent.(Compare intraoperative hemodynamic stability by monitoring SBP, DBP, MAP, HR.)

研究者

发起方
Kranthi Kumar Nannapaneni
申办方类型
Other [Command Hospital Air Force]
责任方
Principal Investigator
主要研究者

Kranthi Kumar Nannapaneni

Command Hospital Air Force Bangalore

研究点 (1)

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