To evaluate the role of optic nerve sheath diameter as a predictor of post dural puncture headache in patients undergoing elective cesarean section; a prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To evaluate the predictive performance of optic nerve sheath diameter as a predictor of post dural puncture headache during elective cesarean section.
研究概览
简要总结
Spinal anesthesia or subarachnoid block is the most preferred choice of spinal anesthesia for cesarean section deliveries as the risk of airway management is avoided and lesser risk of neonatal drug transfer.
post dural puncture headache [PDPH] is a serious and common complication occurring after spinal anesthesia. its incidence ranges from 1% to 36% and occurs mostly within 72 hours after the lumbar puncture is performed. the incidence of PDPH is attributed to CSF leakage through dural puncture site.
the changes in CSF pressure are reflected in optic nerve sheath which is a sheath like structure covered by a meninges and the CSF in subarachnoid space.
the authenticity of using a non invasive ultrasound guided measurement of optic nerve sheath diameter as a clinical parameter for intracranial pressure has been demonstrated.
the ability to predict PDPH can be used to avoid short and long term complications by timely interventions, especially in patients with higher risk factors.
in this study we hypothesize that in patients with multiple risk factors for PDPH monitoring for ONSD might help predict the occurrence of PDPH.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Age 18-40 years 2.ASA score of 2 3.Term 37-42 weeks, singleton pregnancy 4.Elective caesarean section under spinal anaesthesia 5.Informed and written consent provided.
排除标准
- •1.Refusal of patient to take part in the study 2.Hypertensive disorders during pregnancy 3.Contraindications to spinal anaesthesia 4.Local infection of injection site 5.Coagulopathy or other bleeding disorders 6.Severe uncorrected hypovolemia 7.History of allergy to local anaesthetics used 8.Eye diseases especially history of globe rupture and history of visual disturbances 9.Conditions with changes in intracranial pressure (cerebrovascular diseases, haemorrhage, intracranial tumours) 10.Patients undergoing emergency caesarean section.
结局指标
主要结局
To evaluate the predictive performance of optic nerve sheath diameter as a predictor of post dural puncture headache during elective cesarean section.
时间窗: before the lumbar puncture,10 minutes,24 hours,48 hours after the dural puncture and after the surgery
次要结局
- To determine the cut-off point of optic nerve sheath diameter for prediction of Post dural puncture headache(Before dural puncture, 10 minutes,24 hours,48hours after the dural puncture, after the surgery)
研究者
Dr Abhijit PM
Gauhati medical college and hospital