The Effects Of Deep Brain Stimulation Of Subthalamıc Nucleus On Pulmonary Function Tests and Functionality In Patıents With Parkinson's Disease: Short Term Results
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- Mustafa Kemal University
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Functional exercise capacity
- Last Updated
- 7 years ago
Overview
Brief Summary
Parkinson's disease is a progressive chronic neurodegenerative disease. In cases where drug treatment is insufficient and drug use is not possible due to drug side effects, highly effective and low-risk surgical treatment options could be used. In Parkinson's Disease; findings such as chest wall rigidity and weakness of the respiratory muscle strength occur. The aim of this study was to determine the effect of preop and postop DBS surgery on respiratory muscle strength, respiratory function and physical performance in patients with Parkinson's disease.
Detailed Description
In the study, at least 10 patients with Parkinson's disease who had DBS surgery in Mustafa Kemal University Research and Practice Hospital, Department of Brain and Nerve Surgery will be evaluated. Demographic-physical features, pulmonary functions, respiratory muscle strength, exercise capacity, functionality, and muscle strength will be evaluated
Investigators
Bircan Yücekaya
Lecturer
Mustafa Kemal University
Eligibility Criteria
Inclusion Criteria
- •Lack of any neurological disease other than Parkinson's
- •DBS surgery to be performed in the STN region
Exclusion Criteria
- •Patients with advanced cognitive impairment
- •Patients with pulmonary, neurological and orthopedic diseases affecting functionalities
- •Pregnancy
- •Patients in whom the stimulation was canceled due to infection after surgery.
Outcomes
Primary Outcomes
Functional exercise capacity
Time Frame: Change from Baseline Functional exercise capacity at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months
6 minute walking test
Secondary Outcomes
- Muscle strength(Change from Peripheral muscle strength at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months)
- Grip Test (Peripheral muscle strength)(Change from Peripheral muscle strength at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months)
- Pulmonary functions(Change from Pulmonary functions at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months)
- Inspiratory and expiratory muscle strength (MIP, MEP)(Change from Inspiratory and expiratory muscle strength (MIP, MEP) at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months)