Can poor oral health status be a risk factor for unexplained infertility?

Not Applicable

• Conditions: Health Condition 1: K04- Diseases of pulp and periapical tissuesHealth Condition 2: K05- Gingivitis and periodontal diseasesHealth Condition 3: N70-N77- Inflammatory diseases of female pelvic organsHealth Condition 4: O00-O9A- Pregnancy, childbirth and the puerperium

• Registration Number: CTRI/2023/08/056251
• Lead Sponsor: Akshaya Bhupesh Banodkar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Test group

1.Women in the age group of 18-35 yrs

2.Failure to get pregnant despite regular sexual intercourse for more than 12 months

3.Having male partners with a normal semen analysis.

4.Having normal genital organs.

5.Having no pelvic pathology

6.Not receiving any infertility treatment in the past

7.Having a normal hormonal profile.

8.Having adequate follicle reserve

Control group

1.Women in the age group of 18-35 years

2.Women who have conceived naturally within 1 year of planning to conceive.

3.Women in their first trimester of pregnancy

Exclusion Criteria

Test Group

1.Women on infertility treatment

2.Patients who have a history of the following conditions will be excluded; hydrosalpinx, endometriosis, tubal factors, polycystic ovarian syndrome (Rotterdam criteria), inherited thrombophilia, thyroid disease, premature ovarian failure, hyperprolactinemia, autoimmune diseases, diabetes mellitus, uterine/cervical anomalies, active liver disease, cardiovascular disease, smoking and alcohol consumption, HIV-infected, obesity (body mass index >= 30 kg/m2), chronic upper respiratory tract diseases.

3.H/o of dental treatment for dental caries, periodontal treatment, or ongoing orthodontic treatment in the past 6 months

4.H/o administration of systemic antibiotics in the past 6 months

Control group

1.Women in 2nd and 3rd trimester of pregnancy

2.Patients who have a history of the following conditions will be excluded; hydrosalpinx, endometriosis, tubal factors, polycystic ovarian syndrome (Rotterdam criteria), inherited thrombophilia, thyroid disease, premature ovarian failure, hyperprolactinemia, autoimmune diseases, diabetes mellitus, uterine/cervical anomalies, active liver disease, cardiovascular disease, smoking and alcohol consumption, HIV-infected, obesity (body mass index >= 30 kg/m2), chronic upper respiratory tract diseases.

3.H/o of dental treatment for dental caries, periodontal treatment, or ongoing orthodontic treatment in the past 6 months

4.H/o administration of systemic antibiotics in the past 6 months

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
RUSSELL PERIODONTAL INDEXTimepoint: at baseline

Secondary Outcome Measures

Name	Time	Method
ORAL HYGIENE indexTimepoint: at baseline;PUFA indexTimepoint: at baseline