Reported Time Between Onset and Diagnosis of Alzheimer's Disease: Correlation With Objective Parameters
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 129
- 试验地点
- 1
- 主要终点
- Age
研究概览
简要总结
The early diagnosis of Alzheimer's disease is essential to enable patients to have access to the available treatments. However, there is a delay between the diagnosis and the onset of symptoms, which can range from 1 year to more than 5 years. In clinical practice, the hippocampal volume, measured by the Scheltens index, is currently used as a marker of the progression of the disease.
The purpose of this study is to determine whether the patient's sex, age and ethnicity can influence the delay in the expression of cognitive troubles reported by the family at the first medical consultation, as well as to determine if there is a correlation between the delay reported by the family and the Scheltens index.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-
- •Diagnose according to the Dubois criteria
排除标准
- 未提供
结局指标
主要结局
Age
时间窗: Between 01-01-2010 and 31-01-2013
Age
Sex
时间窗: Between 01-01-2010 and 31-01-2013
Sex
Ethnic origin
时间窗: Between 01-01-2010 and 31-01-2013
Ethnic origin
Symptoms-diagnose time interval
时间窗: Between 01-01-2010 and 31-01-2013
Interval of time between the apparition of the first symptoms, as reported by the family, and the diagnose.
Scheltens scale
时间窗: Between 01-01-2010 and 31-01-2013
Evaluation of the hippocampal atrophy by means of magnetic resonance imaging. Scale from 0 (normal) to 4.
次要结局
未报告次要终点
研究者
Murielle Surquin
Head of clinic
Brugmann University Hospital