Assessment of Bioavailability of Phenolics From an Orange Peel Extract

Not Applicable

Completed

• Conditions: Improving Bioavailability

• Registration Number: NCT02033330
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

In this study, the bioavailability of a specific orange peel extract is tested. The composition and morphology of the test product is altered compared to the generic product, which is used as a control. Due to intellectual property issues, more information cannot be given at this moment. Also the difference in bioavailability between a capsule and a lozenge is tested. The hypothesis is that the bioavailability of the altered extract will be improved compared to the control.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07
• Primary Completion: 2013-08
• Status Verified: 2014-01
• Study Completion: 2014-01
• Study First Submitted: 2014-01-09
• Study First Submitted QC: 2014-01-09
• Last Update Submitted: 2014-01-09
• Study First Posted: 2014-01-10
• Last Update Posted: 2014-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

• healthy adults
• BMI 18.5 to 25

Exclusion Criteria

• pregnancy
• smoking
• alcohol or drug abuse
• use of medication
• use of nutritional supplements
• abnormal liver or kidney function

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
plasma concentrations of specific phenolics and their metabolites	up to 24 hours

Secondary Outcome Measures

Name	Time	Method
urine concentrations of specific phenolics and their metabolites	24 hours

Trial Locations

Locations (1)

Maastricht University Medical Centre; 🇳🇱 Maastricht, Netherlands