NCT06722092尚未招募不适用
Can Immersive Virtual Reality Magnify Treatment Outcomes of Script Training on Cantonese Speakers with Chronic Aphasia: a Randomized Controlled Trial
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 105
- 主要终点
- Percentage accuracy of treatment probe correctly produced
研究概览
简要总结
The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes.
The main research questions are:
- Can script training promote verbal functional communication of Cantonese-speaking PWA?
- Can script training enhance nonverbal cognitive functions of Cantonese-speaking PWA?
- Can VR magnify verbal and nonverbal treatment outcomes of script training of PWA?
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
- •premorbid fluent Cantonese speakers,
- •aged between 30 and 80 years,
- •no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
- •no motor speech disorders of moderate to severe level, and
- •normal or corrected-to-normal vision and hearing functions
排除标准
- •concurrent participation in other aphasia treatment trials, and
- •incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.
结局指标
主要结局
Percentage accuracy of treatment probe correctly produced
时间窗: From baseline up to 8-week post training
Participant's production accuracy of the trained scripts in read-aloud and no-cue conditions.
Time to produce each of the scripts in the treatment probe
时间窗: From baseline up to 8-week post training
Participant's production time of the trained scripts in read-aloud and no-cue conditions.
Number of sessions to reach performance criteria in session probe
时间窗: From baseline up to 8-week post training
次要结局
- Cantonese version of the Western Aphasia Battery (CAB) to measure aphasia severity(From baseline up to 8-week post training)
- Cantonese version of the Amsterdam-Nijmegen Everyday Language Test to measure verbal communication effectiveness in conversation via 20 culturally appropriate scenarios(From baseline up to 8-week post training)
- Cantonese version of the 20-item Communication Outcome after Stroke (Can-COAST) as a self-reported outcome on communication and quality of life(From baseline up to 8-week post training)
- Subtest 1 (map search) and 3 (elevator counting) of Test of Everyday Attention to assess attention(From baseline up to 8-week post training)
- Digit span forward and backward task to assess verbal short-term and working memory(From baseline up to 8-week post training)
- Test of Nonverbal Intelligence-third edition (TONI-3) to assess executive function(From baseline up to 8-week post training)
- Wisconsin Card Sort Test (WCST) to assess executive function(From baseline up to 8-week post training)
研究者
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