Incidence and Risk of Influenza in Myasthenic Patients
- Conditions
- Upper Respiratory InfectionMyasthenic Crisis
- Registration Number
- NCT03884777
- Lead Sponsor
- Centre d'Investigation Clinique et Technologique 805
- Brief Summary
Upper respiratory infection , including influenza, may exacerbate the symptoms of myasthenia gravis (MG), which is an autoimmune disease that causes muscle weakness and, in some cases, can precipitate a myasthenic crisis
In the present study, we investigated the incidence and risk factors of influenza infection on in myasthenia gravis patients.
- Detailed Description
This is a descriptive study. The data will be analyzed retrospectively . Inclusion of 416 cases of influenza in myasthenic patients treated in the intensive care unit of Garches Hospital between January 1, 2009 and December 31, 2017.
Patients who meet the inclusion and non inclusion criteria and do not object to participate in the study will be collected in a database for analysis.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 400
- Men or women over the age of 18.
- Myasthenic patients hospitalized in intensive care.
- Patients with confirmed influenza infection
- Age <18 years,
- Other neuromuscular diseases,
- Patient opposing the use of his data
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of influenza in myasthenic patient in crisis between January 1, 2009 and December 31, 2017. Number of influenza cases in myasthenic patients
- Secondary Outcome Measures
Name Time Method Risk factors for poor outcomes between January 1, 2009 and December 31, 2017. To identify risk factors for severe influenza in myasthenic patients