Clinical trial on effect of oral magnesium supplement on lung function in patients with asthma
- Conditions
- Asthma.chronic lower respiratory disease
- Registration Number
- IRCT2012102811285N1
- Lead Sponsor
- Abadan International Unit Of Ahwaz Jundishapur University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Men and women 19 to 55 years of age who met the Global Initiative for Asthma (GINA) guidelines in 2008, FEV1more than80%, variability FEV1less than 20-30% for mild asthma and FEV1=60-80%, variability FEV1more than 30% for moderate asthmatic; non smoker; who used only beta-agonist or inhaled corticosteroids.
Exclusion criteria: evidence of cardiovascular disease, abnormal kidney function,other lung disease; alcohol abuse; uncontrolled hypertension; pregnancy or breastfeeding; have any change in own diet; current use of theophyline or leukotriene antagonists; any treatment likely to affect magnesium absorption or excretion, including diuretics or calcium containing medications; history of emergency room care or hospitalization for asthma in the last 6 months.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Force Vital Capacity. Timepoint: before intervention and two months after the intervention. Method of measurement: based on litter with spirometry.;Forced expiratory volume in one second. Timepoint: before intervention and two months after the intervention. Method of measurement: based on %liter with spirometry.;Density of interlukine 17 in blood. Timepoint: before intervention and two months after the intervention. Method of measurement: based on pico grams per milliliter with laboratory kit.;FEV1/FVC. Timepoint: before intervention and two months after the intervention. Method of measurement: with spirometry.
- Secondary Outcome Measures
Name Time Method Magnesium concenteration in serum. Timepoint: before intervention and two months after intervention. Method of measurement: based on mg/dl with laboratory kit.;Level of magnesium intake. Timepoint: three times (two days and one weekend). Method of measurement: based on mg/d with 24 hours intake for three times.;Levels of quality of life. Timepoint: before intervention and two months after intervention. Method of measurement: numbers of quality of life quationnaire.;Level of asthma control. Timepoint: before intervention and two months after intervention. Method of measurement: numbers of asthma control quationnaire.