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Evaluation of the Efficacy and Tolerance of Plasmapheresis by Double Cascade Filtration in a University Centre

Completed
Conditions
Kidney Failure
Registration Number
NCT04261205
Lead Sponsor
Centre Hospitalier Universitaire de Nīmes
Brief Summary

A study is being carried out to evaluate the biological, technical and clinical/biological efficacy of this technique, the practice of which is standardized in the department, in order to evaluate our practices and to improve them if necessary. As part of this study, the investigators will ask all patients scheduled for this procedure to participate in this observational prospective study without changing usual practices.

Detailed Description

The objective of the study is to conduct a prospective evaluation of the practice of apheresis by Double Filtration System Cascade system in a university centre in current practice with evaluation of the technical and biological effectiveness as the main objective and clinical and biological tolerance as the secondary objective for all consecutive sessions performed in a university centre over a period of 1 year.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
70
Inclusion Criteria

Over 18 years of age I indication for plasmapheresis and hospitalized at Chu de Nimes.

Exclusion Criteria

Under guardianship or curatorship Refusal to participate

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Apheresis by DFPP and biological efficiencyover a period of one year

quantification of the purification carried out (volume)

Secondary Outcome Measures
NameTimeMethod
variation of Hb, platelet and albumin before and after sessionwithin 1 hour of all session

% of Hb, platelet and albumin

Biological side effectswithin 1 hour of all session

Bleeding rate

Clinical side effectswithin 1 hour of all session

catheter dysfunction

Trial Locations

Locations (1)

CHU de Nîmes, Hôpital Universitaire Caremeau

🇫🇷

Nîmes, France

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