Effects of Jianpi Lushi Jiedu Formula on postoperative recurrence of colorectal adenoma with spleen deficiency and dampness syndrome and its mechanism based on IL-6/JAK/STAT3 signaling pathway
- Conditions
- Colorectal adenoma
- Registration Number
- ITMCTR2200006127
- Lead Sponsor
- anjing Hospital of Integrated Traditional Chinese and Western Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1) The colorectal polyp was diagnosed by colonoscopy. The histopathologic examination was consistent with adenoma, and the adenoma had been excised or resected by endoscopy,in addition to treatment, and TCM syndrome in line with the spleen-deficiency syndrome of damp-toxin patients;
2) Age from 18 to 75, male or female;
3) The patients gave full informed consent and accepted the observation completely voluntarily, and signed the informed consent form.
1) It does not accord with the diagnostic standard of colorectal polyp or the diagnostic standard of TCM syndrome of adenoma or damp-toxin syndrome of spleen deficiency by pathology;
2) A pregnant or lactating woman or a person preparing to give birth;
3) Allergic constitution or allergic to many kinds of drugs;
4) Patients with severe heart, lung, liver, kidney and blood system diseases;
5) The patients with suspicious canceration or canceration have been examined by biopsy;
6) Patients who took the drug or were in another clinical trial within 1 month.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Recurrence rate of colorectal adenoma;
- Secondary Outcome Measures
Name Time Method An indicator of inflammatory cytokines;Protein expression index of colon tissue;Protein expression index of colon tissue;